Darwin in the genome: molecular strategies in biological evolution

Darwin in the genome: molecular strategies in biological evolution
by: Lynn Helena Caporale

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type: .pdf
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language: en [ english ]
submitted by: anonymous



year: 2003
pages: 258
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paginated: yes
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Smart genomes--an enthralling account of revolutionary discoveries at the cutting edge of genomics research Written by a molecular biologist at the forefront of genomics research, Darwin in the Genome is an exciting account of one of the hottest new theories in biology today: evolution by natural selection inevitably leads to strategic mutations. In the struggle for survival, from pathogens to flowers, birds to orangutans, baker's yeast to people, the fittest genomes are those that evolve effective molecular strategies that respond to, and in fact anticipate, challenges and opportunities in their environments. Writing in a clear, accessible style, Lynn Caporale describes the emergence of genomic mutation strategies, which researchers are just beginning to uncover. She also spells out some of the more profound implications of these findings, including the importance of biodiversity, indeed human diversity, for survival, the possibility of bold new directions for medical research, and the inherent dangers of attempting to fix perceived "errors" in a human genome.

Prologue Chance Favors the Prepared Genome
Chapter 1 Diversity or Death
Chapter 2 The Magic Staircase
Chapter 3 Predators Battle Prey in the Genome
Chapter 4 Mutation Is Not Monotonous
Chapter 5 What the Antibody Genes Tell Us
Chapter 6 Slippery DNA and Tuning Knobs
Chapter 7 Everyone Has Something to Teach Us
Chapter 8 The Genome Sends an SOS
Chapter 9 Journeys through Space and Time
Chapter 10 Strategies as Targets, Round One: The Pathogens
Chapter 11 Strategies as Targets, Round Two: Cancer
Chapter 12 Theme and Variations
Chapter 13 Family Heirlooms: A Framework for Evolution
Chapter 14 Interchangeable Parts
Chapter 15 Jumping Genes
Chapter 16 Be Prepared for the Unexpected
Chapter 17 Mixing Up Genes for the Children
Chapter 18 Sculpting the Genome
Chapter 19 Decoding DNA
Epilogue What Became of the First Genome?
About the Author

Common terms and phrases:
amino acids antibody bacteria bacterium CCR5 chromosome codons cone snails DNA sequences double helix enzyme immune system introns jumping genes meiosis mutation pathogen transposons